Post-doctoral Scientist in Cancer Immunology
The project which is funded by the MRC will explore the role of the PI3K pathway in T cells and how this can be manipulated to increase anti-tumour responses, particularly in the context of cancer metastasis.
The successful applicant will join a friendly and collaborative team of researchers with access to cutting-edge facilities and resources within the centre of Cambridge on the historic Tennis Court Road site. The applicant will gain exposure to experimental approaches in cellular and molecular immunology including conditional mouse genetics, in vivo genetic cell fate-tracking, molecular biology and high throughput RNA- and DNA-sequencing. The applicant will also have the opportunity to develop CRISPR/Cas9-based mutagenesis screens to discover novel mechanisms of immune suppression in the metastatic tumour microenvironment. The programme of work is based on a collaboration with the Roychoudhuri Group whose lab is next to the Okkenhaug lab, as well as with futher collaborations with the Thaventhiran group (MRC tox) and Halim group (CRUK CI).
The ideal candidate will be motivated, independent and enthusiastic, and have a PhD in immunology, cell biology, or a related field.
Experience with flow cytometry, cell culture, and molecular biology techniques and a track record of publications in peer-reviewed journals are desirable. Strong analytical and problem-solving skills, written and verbal communication skills, and the ability to work independently as well as part of a team are desirable. Having a Home Office Personal licence (PIL) or equivalent and experience with cancer models will be an advantage.
Fixed-term: The funds for this post are available for 5 years in the first instance.
Application deadline: Jan 31, 2023.
https://www.jobs.cam.ac.uk/job/44318/
For informal inquires about postdoctoral positions in the Okkenhaug lab, please contact Klaus Okkenhaug (ko256@cam.ac.uk). Please include a paragraph of why you want to join our laboratory and whether you have considered possible sources of funding, e.g. for Fellowships.
Prospective PhD students: please check eligibility and application procedures here.
Further information also available here: https://www.postgraduate.study.cam.ac.uk/courses/directory/blpapdpth